July 1999 JOURNAL OF THE CALIFORNIA DENTAL ASSOCIATION
Impressions
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Integrating the Arts

By David G. Jones


Dentists can play an even larger role in the overall health of their patients by paying attention to visual and other clues that could indicate serious underlying medical conditions, suggests a recent study.

Arthur H. Friedlander, DDS, professor of oral and maxillofacial surgery at the UCLA School of Dentistry, and Michael Littner, an MD pulmonologist at the Veterans Administration Medical Center in Sepulveda, are two of four researchers who collaborated on a study that for the first time uncovered a particular link between sleep apnea and an increased risk of stroke. It also showed that the estimated 9 million adult Americans who suffer from obstructive sleep apnea are three times more likely to have diabetes. Their work was published in the May issue of the Journal of Oral and Maxillofacial Surgery.

Friedlander, also the associate chief of staff for graduate medical education at the VA medical center, said he undertook the study because he has long been interested in dentists viewing panoramic radiographs and looking for carotid arterial blockages. By 1994, Friedlander started looking at high-risk patient groups.

"That led me to patients with obstructive sleep apnea, because we already knew that they suffered from strokes at a higher rate than the average population," he says.

Littner, who also serves as a professor of medicine at the UCLA School of Medicine, also knew of studies that showed that strokes are more common in people with obstructive sleep apnea, but he said a direct correlation had not yet been proven.

"Dr. Friedlander had an interest in the cause of strokes, and as a pulmonologist I had an interest in sleep apnea, so we collaborated with my patients who were already diagnosed with sleep apnea," Littner says. "The patients exhibited an increased prevalence of cardiovascular problems with sleep apnea. The question became, 'Why?'"
Littner said the medical literature was not clear, so the researchers set about to discover a specific link.

"We started to take panoramic radiographs of the patients, and we found large numbers to have evidence of blockages of their carotid arteries," he says.

The researchers took panoramic X-rays of 54 randomly selected male veterans who had previously been diagnosed with obstructive sleep apnea. Examination of the X-rays showed that 12 of the 54, or 22 percent, had calcified plaques in the carotid artery leading to the brain. The researchers also tested the patients' blood sugar, which revealed that 17 of the 54, or 31 percent, unknowingly suffered from adult-onset diabetes.

"No one had discovered the fact that patients with obstructive sleep apnea have a higher risk of Type II diabetes," Friedlander says. "No one had looked systemically at patients as we did."

The study, that began in mid-1995 and finished near the end of 1997, also showed how dentists can play an increasingly important role in the general health of their patients. Lee V. Heldt, DDS, MD, president of the California Association of Oral and Maxillofacial Surgeons, says that is a logical step beyond the normal screening process dentists use with patients.

"This is a step forward from that, and if dentists can identify a pattern of calcification of the carotid artery, it would certainly be appropriate to refer the patient for a cardiovascular workup," he says. "Of course the other question it raises is the importance of reviewing the past medical history a little further and asking some questions about the quality of sleep, which could prompt a separate consultation for sleep disturbance."

James E. Eckhart, DDS, contributing editor to the August 1998 CDA Journal issue on snoring and sleep apnea, said the study could help raise dentists' awareness.

"It could make dentists more alert to the relationships between obstructive sleep apnea, stroke and carotid blockage, and help the patient seek medical attention to prevent stroke when a blockage is suspected," he says.

Friedlander outlined other clues that could indicate that a patient is at risk for sleep apnea and an underlying and undetected diabetes or predisposition to cardiovascular problems. He said obesity; a thick neck; excessive fat in the palate, tongue and pharynx; an enlarged tongue; a long soft palate; and a small retrognathic mandible are all indicators for obstructive sleep apnea.

According to Eckhart, the information illustrates the value of the panoramic X-ray.

"Patients can benefit by dentists screening suspected obstructive sleep apnea patients with panoramic films to detect possible blockages," he says. "The fact that particularly in older patients carotid blockage can be viewed on a panoramic radiograph may be an additional reason to obtain one of these systems."

Friedlander considers the study's results exciting.

"I think what this material does is more closely align dentistry with aspects of preventive medicine, in which we can identify patients at risk of stroke and help them get needed treatment," he concludes.




Tasteful Dressing

Staff personal appearance is an important part of how patients perceive a dental office. In the May 1999 issue of Dental Economics, Janice Hurley and Jana Tristao offer tips for maintaining the professional look.

They write that the best time to bring up the topic of appropriate dress is during the interview process, but that the subject can be broached with staff at any time. Two important areas should be discussed:

* The value of consistency. If how a potential staff member has dressed for the interview is appropriate for the office, the dentist should mention it and stress the importance of consistently dressing that way. The interviewee should be asked if dressing that way every day is something he or she will be able to do.

* The office's written grooming standard. Having a written policy for both front- and back-office staff is important for projecting a professional image. If what is appropriate is written in detail, it will be easier for staff to follow.

The authors also suggest that a dentist consider investing in staff office wardrobes. If a dentist chooses to do so, they suggest discussing the policy with staff, agreeing on the type of purchases before they are made and setting a dollar figure of about $500 per person.


Giving Patients a Fair Hearing

With 400,000 deaf people in America, chances are good that a dentist will encounter a deaf or hard-of-hearing person in the office. An understanding of the needs and limitations of deaf patients is important, write Claudia Schmitz, RDH, and Sandra Volkman, RDH, in the January 1999 issue of Access, a publication of the American Dental Hygienists Association.

When communicating with a hard-of-hearing person, the first step is to determine which communication method the patient prefers. There are several options, but many have limitations.

* Lip-reading. Only a small percentage of deaf people can lip-read; and, in even the best of circumstances, only a small part of what is said is understood.

* Writing. Writing can be awkward, especially when scientific terms are involved. Also, for many deaf people, English is a second language.

* American Sign Language. Even hearing people who can use ASL may not interpret responses correctly.

* Interpreter. Hiring an interpreter is the ideal solution to the problem of communicating with the deaf, according to the authors. They note that dentists might have to provide an interpreter by law because the Americans With Disabilities Act states that an interpreter must be provided for a client who requests one. Sign language interpreters certified by the Registry of Interpreters for the Deaf are available in every state and most large cities.

For communicating with a deaf patient when he or she is outside the office, e-mail and the teletypewriter are suggested.


A Key to Cleft Palate is Discovered

Researchers led by a team of University of California at San Francisco scientists have identified the mechanism by which cleft palate -- the most common craniofacial birth defect in humans -- wreaks its havoc.

Earlier research had already established that abnormalities in the gene for Transforming Growth Factor Alpha (TGF-a) were linked to cleft lip and palate syndromes. TGF-a is a growth factor with many known functions, yet how it related to cleft palate had been a mystery.

The inter-institutional group, led by Rik Derynck, PhD, UCSF professor of cell biology in the Department of Growth and Development, and Zena Worb, PhD, UCSF professor of cell biology in the Department of Anatomy, demonstrated that during normal embryonic development, docking of the molecule TGF-a with the Epidermal Growth Factor Receptor (EGFR), results in the production of a class of proteins called matrix metalloproteinases (MMPs).

Using mice specially bred without the EGFR, the researchers learned that after activation of the EGFR, MMPs regulate the closure of the palate. Palate closure must be closely coordinated with the development of the lower jaw, a process regulated by MMPs. Simply put, if EGFR does not function properly when TGF-a joins with it, MMPs are not produced and cleft palate frequently results.

The study is reported in the May 1999 issue of the journal Nature Genetics.


ADA Survey Center Offers New Reports

Recently released reports available from the ADA Survey Center include:

* Annual Expenses of Operating a Dental Practice -- With statistics for 24 categories of expenses for independent dentists, solo dentists, independent non-solo dentists and new dentists.

* Five reports from the 1996 Dentist Profile Survey -- Each covers a single racial or ethnic group and includes information on family and personal concerns, work-related issues and practice characteristics.

* Dentists in Solo and Non-Solo Practice -- This report from the 1997 Survey of Dental Practice compares various aspects of both types of dental practice, including income, gross billings, expenses and time spent in the practice.

For more information call (312) 440-2500, Ext. 2568.


UCSF Receives Record Donation

The UCSF School of Dentistry has received a bequest of $6.5 million, the largest single gift in the dental school's history.

The bequest came from the estate of Gladys Barber of San Francisco. Her deceased husband, Leland, was a member of the school's class of 1919.

The gift will be used to establish two Leland A. and Gladys K. Barber Distinguished Professorships in Dentistry, each funded at $2.5 million. The balance of the bequest will be used to fund an endowed chair.


Some Cancer Patients Look for Alternatives

Researchers studied 200 patients with head and neck cancer to determine the prevalence of the use of alternative therapies and the demographics of the patients using alternative medicine. The researchers found that alternative therapies were used to specifically fight cancer directly and as an adjunct to conventional treatment, rather than to treat the adverse effects of conventional treatment.

A majority of patients limit or avoid the use of alternative medicine based on discouragement from their physicians and a lack of solid medical evidence, the researchers write. Patients believe their physicians to be the most knowledgeable source of information about alternative therapies.

Alternative Medicines Used

Herbal medicines -- 50.7 percent

Pharmacological treatments -- 16.9 percent

Manual healing -- 10.1 percent

Diet and nutrition -- 8.7 percent

Mind-body techniques -- 7.7 percent

Traditional and folk remedies -- 5.8 percent


Honors

Eugene Manusov, DDS, and Eugene Sekiguchi, DDS, were presented with the 1999 Distinguished Community Service Award from the Anti-Defamation League at its recent Dental Division Dinner.

Mahmoud Torabinejad, DDS, MSD, PhD, has been elected treasurer of the American Association of Endodontists. James A. Abbott, DDS, MS, has been elected to the Board of Directors of the same organization.

Albert Solnit, DDS, has been awarded the Pierre Fauchard Honor Award by the Pierre Fauchard Academy's Southern California Section. (have photo)

Peter L. Jacobsen, PhD, DDS, professor and director of the Oral Medicine Clinic at the University of the Pacific School of Dentistry, has received the 1999 Gordon J. Christensen Lecturer Recognition Award. (photo)


Upcoming Meetings

1999

Sept. 1-4 Surfaces in Biomaterials '99, Scottsdale, Ariz., (612) 512-9103

Sept. 2-4 Academy of Surgical Research Annual Meeting, Scottsdale, Ariz., (612) 545-1919

Sept. 16-18 CDA Scientific Session, San Francisco, (916) 443-3382, Ext. 4470

Sept. 17-18 Society for Advanced Dentistry Annual Meeting, New Orleans, (317) 290-2613

Sept. 25-29 American Academy of Periodontology Annual Meeting, San Antonio, Texas, www.perio.org

Oct. 28-Nov. 1 FDI Annual World Dental Congress, Mexico City, +44 171 935 7852

2000

April 6-8 Dentistry 2000 -- British Dental Association Annual Conference and British Dental Trade Association Dental Showcase Exhibition, Birmingham, England, 01934 844408

April 13-16 CDA Scientific Session, Anaheim, Calif. (916) 443-3382, Ext. 4470

Sept. 17-20 American Academy of Periodontology Annual Meeting, Honolulu, www.perio.org.

To have a meeting included on this list, please send the information to Upcoming Meetings, CDA Journal, P.O. Box 13749, Sacramento, CA 95853 or fax the information to (916) 443-2943.



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